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BCBM-RadioGenomics, breast cancer brain metastases

Post-contrast T1 MR of the brain, skull-stripped, of a patient treated with Gamma Knife radiosurgery for brain metastases of breast cancer at the University of Minnesota, every metastasis outlined for the treatment (BCBM-RadioGenomics, TCIA).

13 test casesbrainimage MR
Read before comparing (7)
  • Pool. 165 patients treated with Gamma Knife radiosurgery for brain metastases of breast cancer, 268 sessions; a case is the first session, <patient>-0. 134 patients are in the pool. Held out by the names of their masks: 9 with a resection cavity, 1 with a planning target, 19 with a name that may be an organ at risk or a lesion (a bare 'pons', 'cerebellum', 'vermis', 'thalamus', 'AN'...), and 2 whose sessions start at 1; BCBM-RadioGenomics-169, drawn for development, because one of its masks is a larger region round another.
  • Images. The provider's post-contrast T1, skull-stripped with HD-BET and bias-corrected with N4: 0.5 x 0.5 x 1 mm on the drawn cases, values without unit, 0 outside the brain. 1.5 and 3 T scanners. No mask is given.
  • Truth. The contours drawn for the treatment, made and reviewed by at least one neurosurgeon and one radiation oncologist, one mask a structure named freely. Every mask but the organs at risk (brainstem, optic nerves and chiasm, cochleae, orbits, lenses, pituitary stalk) is a metastasis, merged into one label. On the drawn cases the masks lie on the image's grid and read 1.1 to 2.8 times brighter than the brain on average, save a cystic cerebellar lesion of BCBM-RadioGenomics-65; all but two of those whose name gives a side lie on that side, the two near the midline. Graded expert.
  • Lesions. The test cases hold 1 to 10 metastases, 0.07 to 11 mL in all (median 4.0 mL); 15 of the 41 test lesions are under 0.1 mL, so small lesions weigh on the Dice.
  • Start. Over the 13 test cases a whole-image mask scores a Dice of 0.0007 at the median, an Otsu mask 0.0066.
  • Overlap. The patients are the University of Minnesota's; no other descriptor names the collection or Minnesota brain data. UCSDBrainMets (UC San Diego), BrainMetsMR and BrainMetsLungMR (Yale) are other hospitals' cohorts.
  • Outside numbers. None: the collection has no challenge and no official split.

No method has a result on every case of this dataset yet.

Case by case

Click a score to look at that result: the image, the truth in green and the method's map in red. Underlined scores have their image; for the others you see the case without the result.

About the data

Test cases
13 test patients drawn with seed 2026 among the 121 outside development, then 12 development patients, the last of the same seeded order. A case is a patient's first radiosurgery; one hospital, so no strata. The notes say which patients are held out.
Truth
contours by experts every metastasis contoured for the patient's first radiosurgery, by or with a neurosurgeon and a radiation oncologist, merged into one label; the organs at risk drawn beside them are left out
Licence
CC BY 4.0
12 cases for tuning, never tested

BCBM-RadioGenomics-69, BCBM-RadioGenomics-57, BCBM-RadioGenomics-72, BCBM-RadioGenomics-114, BCBM-RadioGenomics-17, BCBM-RadioGenomics-122, BCBM-RadioGenomics-127, BCBM-RadioGenomics-67, BCBM-RadioGenomics-155, BCBM-RadioGenomics-37, BCBM-RadioGenomics-173, BCBM-RadioGenomics-157