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nnsyn

nnsyn, CSIRO AEHRC's nnU-Net ResEnc-L that regresses the CT (team KoalAI, first in SynthRAD2025's MR-to-CT task), with its authors' released SynthRAD2025 models, one per source modality and region, run as their challenge docker runs them on the one fold they published.

SynthesisGPUversion nnsyn af36483; fold 0 of huggingface.co/aehrc/Synthrad2025_task1 (ee17646) and aehrc/Synthrad2025_task2 (30da517), SHA-256 checked; CT de-normalisation of aehrc/synthrad2025_docker (25cbfe7)every datasetApache-2.0

Run it

With its KonfAI app, at the benchmark's settings (the fidopt app repositories are private for now: a Hugging Face token with access opens them):

pip install konfai-apps
modelCommand
CBCT to CT, head and neckGet the appkonfai-apps infer fideus-labs/fidopt-synthesis:nnsyn_CBCT_HN -i image.nii.gz -o out --gpu 0
CBCT to CT, thoraxGet the appkonfai-apps infer fideus-labs/fidopt-synthesis:nnsyn_CBCT_TH -i image.nii.gz -o out --gpu 0
CBCT to CT, abdomenGet the appkonfai-apps infer fideus-labs/fidopt-synthesis:nnsyn_CBCT_AB -i image.nii.gz -o out --gpu 0
MR to CT, head and neckGet the appkonfai-apps infer fideus-labs/fidopt-synthesis:nnsyn_MR_HN -i image.nii.gz -o out --gpu 0
MR to CT, thoraxGet the appkonfai-apps infer fideus-labs/fidopt-synthesis:nnsyn_MR_TH -i image.nii.gz -o out --gpu 0
MR to CT, abdomenGet the appkonfai-apps infer fideus-labs/fidopt-synthesis:nnsyn_MR_AB -i image.nii.gz -o out --gpu 0

Results

Datasetmodel#Read byScoreFailedTime s
Head Neck CBCT to CT (HUST)CBCT to CT, head and neckMAE201.7013
HaN-Seg, T1 MR to CTMR to CT, head and neckMAE101.6034
ICASSP-2024 3D-CBCT challenge, simulated low-dose CBCT to CTCBCT to CT, thoraxMAE311.60
4D-Lung, CBCT to CTCBCT to CT, thoraxMAE66.80
Paired head CT and MR, MR to CTMR to CT, head and neckMAE142.70
Pelvic-Reference-Data, CBCT to CTCBCT to CT, abdomenMAE45.40
Simulated CBCT to planning CT, LCTSCCBCT to CT, thoraxMAE353.3022
SynthRAD2023, CBCT to CT, brainCBCT to CT, head and neckMAE98.4015
SynthRAD2023, MR to CT, brainMR to CT, head and neckMAE131.80
SynthRAD2023, CBCT to CT, pelvisCBCT to CT, abdomenMAE100.50
SynthRAD2023, MR to CT, pelvisMR to CT, abdomenMAE92.9032
Source
github.com/aehrc/nnsyn/tree/af364831c57353490989b3652e09dd4b8aa0f250
Reference
Rogowski et al., SynthRAD2025 challenge report, arXiv:2605.13555 (2026), team KoalAI