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ISLES 2022, diffusion to FLAIR

The diffusion-weighted brain MR (b=1000) and ADC map of a patient with an acute or sub-acute ischaemic stroke, and the FLAIR of the same session, registered onto them by the corpus, as the target (ISLES 2022 training set, Munich and Bern).

20 test casesbrainsource DWI and ADC, target FLAIRresearch only
Read before comparing (6)
  • Pool. ISLES 2022's 250 training cases, one MR session of one patient each, from clinical routine: 198 at the University Hospital of the Technical University of Munich, 52 at the University Hospital of Bern.
  • Source. The DWI at b=1000 and its ADC map as delivered, skull-stripped, as channels dwi and adc: Munich's resliced by the provider to 2 mm, Bern's as acquired (1.15 or 1.8 mm in plane, 4.8 mm slices).
  • Target. The FLAIR of the same session, which the provider does not register: the corpus registers it rigidly onto the DWI (mutual information) and resamples it once onto the DWI's grid, so it is smoother than the FLAIR as acquired. The two skull-stripped brains overlap at a Dice of 0.996 at the median of the 38 cases (0.975 to 0.999), against 0.979 in the scanner frame; two development cases keep the scanner frame, where the registration did not improve that overlap: strokecase0207, whose registration drifted 13 mm, and strokecase0087, about 1 mm off. A re-registration of the built test cases finds at most 1.1 mm left (median 0.3). Graded automatic and ranked apart: what the registration leaves counts as error for every method.
  • Intensities. No unit, and the FLAIR's scale changes with the scanner: its median in the mask runs from 149 to 1213 over the test cases. truth.dynamic_range is 1970, the median of the test targets' 99.9th percentiles inside the mask (271 to 2310), one range for the PSNR and SSIM, loose on the low-scale scanners.
  • Baseline. Inside the mask of the test cases a constant at each target's median scores an MAE of 222 on average (31 to 365), a PSNR of 18.0 dB (12.2 to 33.1) and an SSIM of 0.401 (0.247 to 0.810).
  • Overlap. ISLES2024's Munich patients include ISLES 2022 ones: each drawn Munich case's DWI was matched, after an affine registration, against the follow-up DWI of the 33 Munich patients of ISLES2024 and ISLES24_NCCTCTA_Syn. strokecase0076 is ISLES2024's stroke0036 (Pearson r 0.991) and is held out; the other 990 pairs reach 0.673 at most (the same check scores a moved and resampled ISLES 2022 DWI at 0.995). None of Bern's 52 ADC maps shares a grid with ISLESOutcomeMR's (ISLES 2017, Bern and Freiburg, 2005 to 2015), a check that finds ISLES 2016's 30 training maps in ISLES 2017 at r 1.000; a patient scanned in both periods cannot be ruled out without dates.

No method has a result on every case of this dataset yet.

Case by case

Click a score to look at that result: the target image, and over it the method's synthetic image. Underlined scores have their image; for the others you see the case without the result.

About the data

Test cases
The challenge's 150 test cases are hidden. 20 test cases drawn with seed 2026 among the 203 training cases left (16 Munich, 4 Bern, the centres in proportion) and 18 development cases; held out are ISLES2022's 46 test and development cases, whose DWI its methods are given, and strokecase0076, a patient of ISLES2024.
Truth
target image by a program the same session's FLAIR after the corpus's rigid registration and cubic B-spline resampling onto the DWI's grid, in the scanner's units
Licence
CC BY 4.0
18 cases for tuning, never tested

strokecase0203, strokecase0114, strokecase0207, strokecase0190, strokecase0221, strokecase0041, strokecase0087, strokecase0248, strokecase0103, strokecase0051, strokecase0171, strokecase0062, strokecase0195, strokecase0111, strokecase0012, strokecase0182, strokecase0074, strokecase0216